Supply, delivery, installation, and servicing of one glove box - national res...

• Closing date: 25 November 2026 at 11:00 am
• No briefing session or site visit is scheduled.

• Contact: SCM Team (Supply Chain Management Section)
• Email: [email protected]
• Telephone: not stated
• Submission address: Tender Box, Main Security Gate, iThemba LABS, Old Faure Road, Faure, Western Cape, 7131
• Email submission: [email protected]
• Fraud reporting: toll-free 0800 701 701 or SMS 39772

Submission method: sealed bid box or email

• Bid box address: Tender Box, Main Security Gate, iThemba LABS, Old Faure Road, Faure, Western Cape, 7131
• GPS: 34.025°S 18.716°E; tender box opening 300 mm x 20 mm
• Email submission: [email protected]
• Mark the envelope face with the bid number, bidder name, postal address, contact name, telephone number and email address.
• Two-envelope system: Envelope 1-Part A (Bid Forms and Compliance Response) and Part B (Technical Response); Envelope 2 (Financial Proposal and Bid Submission Form). No financial information in Envelope 1.

Returnable documents (must be signed and completed):

• SBD 1 (Invitation to Bid): bidder details and bid offer; also serves as tax compliance questionnaire.
• SBD 4 (Bidder's Disclosure / Declaration of Interest): discloses any state employment or relationships with the NRF or bid participants.
• SBD 6.1 (Preference Points Claim): claims B-BBEE preference points; attach a B-BBEE certificate or sworn affidavit.
• Resolution granting the signatory authority to bind the company, unless the signatory is owner, partner or managing director.
• SBD 3.2 (Pricing Schedule) in the prescribed format, placed in a separate envelope.
• At least one contactable reference for a prior supply of a GMP-compliant glove box for an At-211 synthesis unit.
• Completed specification checklist responding "Yes" or "No" to every mandatory requirement, with alternatives for any "No" response.
• Presentation of the proposed system elements.

Disqualification risks:

• Failure to respond to all specification items; any "No" without a stipulated alternative.
• Missing or unsigned mandatory returnable documents.
• Attempting to influence evaluation, comparison or award decisions.
• False, misleading or incomplete declaration of interest.
• Fronting; bidder must disprove within 7 days of notification, otherwise the bid is invalidated and the bidder may be barred for up to 10 years.
• Counter proposals are not accepted.
• Bids received after the closing time.

Three-stage evaluation:

• Stage 1 (Administrative): compliance with CSD registration, SBDs and returnable documents as listed in Part A. Failure disqualifies.
• Stage 2 (Technical): evaluation against the technical specifications and Mandatory Qualification requirements. Presentation of proposed system elements required. Failure to meet the technical minimum disqualifies.
• Stage 3 (Scoring): points awarded on price via SBD 6.1 in accordance with the PPPFA 2000 and its 2022 Regulations.

The bidder with the highest combined score is nominated for award, subject to completion of administrative documentation.

No minimum qualifying score, no functionality score and no 80/20 or 90/10 split are stated.

Supply, delivery, installation, commissioning and annual servicing of one glove box to contain a GMP-compliant Astatine-211 synthesis module at iThemba LABS, Faure.

Mandatory technical requirements:

• Must meet the CE certification requirements of a GMP-compliant 211At synthesis module.
• Ventilated work compartment to contain 211At vapour and particles for operator protection.
• Compartment hosting the synthesis module: minimum 1200 mm x 660 mm x 850 mm (L x W x H).
• Must support the synthesis unit weight of 40 kg plus additional equipment such as a 25 kg dose calibrator.
• Pass-throughs: one power cable (EU input), one nitrogen gas line (1/8" OD FEP tubing, ~1 m internal length), one ethernet data cable (direct connection, no routers or converters), one additional blind power, one additional gas line.
• Replaceable, non-flammable work floor material (e.g., tray).
• At least three gloves with centre pitch 35-45 cm; glove centres 30-35 cm above the module surface; butyl rubber with melting point above 105°C and resistant to chloroform.
• Minimum 20 cm clearance between any synthesis unit panel and the closest wall; minimum 30 cm between furnace top and compartment ceiling (synthesis unit: 605 x 435 x 535 mm).
• Front door or removable panel opening of at least 650 mm x 550 mm for module installation; door must stay open and be designed to prevent head injury.
• Material pass-through: approx. 25 cm x 25 cm x 45 cm (W x H x D), door openings at least 20 cm x 20 cm, capable of carrying a 30 kg shielding container; sliding doors and dedicated ventilation.
• Air exchange: minimum 20 air changes per hour; bidder to propose and supply solution verified by iThemba LABS radiation safety division.
• Exhaust venting to HVAC or alternative complying with local radiation safety standards, to avoid overheating.
• Intake and exhaust filtration: carbon filters for operator protection and HEPA filters for product protection.
• Manual shut-off valves on intake and exhaust for pressure integrity testing (e.g., EN 12469) and emergency isolation.
• Work compartment differential pressure maintained at -40 Pa relative to surrounding lab; differential pressure gauge with alarm.
• Radiation dose monitoring system inside the compartment.
• Lighting of at least 500 Lux at the front, especially in front of the synthesis unit.
• Provision for a dose calibrator (ionization chamber) inside the work area, compatible with the synthesis unit's space and distance requirements.
• Space for the control laptop outside the compartment (e.g., holder tray), larger than 375 mm x 30 mm x 273 mm, positioned for simultaneous hands-on work and screen viewing.

Other requirements:

• Training of glove box operators by the bidder.
• IQ and OQ on installation; supply of full IQ, OQ and PQ documentation, test protocols, results and certificates.
• Annual servicing and qualification for five years, plus repairs and remote support as needed.
• Bidder to supply these solutions: air exchange, venting, filtration, differential pressure control – each verified for suitability by iThemba LABS radiation safety division.

• Bidder must provide at least one contactable reference for supplying a GMP-compliant glove box suitable for containment of an Astatine-211 (Atley C100 or similar) synthesis unit.
• Bidder must complete the specification checklist with "Yes" or "No" for every mandatory requirement; any "No" must be accompanied by an alternative.
• Bidder must train glove box operators.
• Bidder must provide annual servicing and qualification for five years, plus ad-hoc repairs or remote support.

• Glove box must be CE-certified for a GMP-compliant 211At synthesis module.
• Must meet radiation safety standards and certifications required for operation.
• IQ and OQ must be performed on installation; full documentation, test protocols, results and certificates for IQ, OQ and PQ must be supplied.
• Annual service and qualification for five years.
• iThemba LABS may conduct site visits and inspections during the contract period.

• Use SBD 3.2 Pricing Schedule in the form provided in the bid document.
• Pricing must be placed in a separate envelope (Envelope 2) with no financial information in the technical envelope.
• Prices quoted are fixed for the contract term; adjustments only for incidental services, VAT changes and exchange rates.
• Where applicable, separate overseas and local cost components.
• iThemba LABS provides bidding estimates of quantities for ceiling price calculation.
• Performance security: financial bond required if an upfront deposit exceeds R 1 million.
• Payment within 30 days of invoice.

• Payment: within 30 days of receipt of invoice following successful delivery, or earlier if accompanied by signed iThemba LABS delivery validation documents.
• Performance security: a financial performance bond equal to any upfront deposit above R 1 million; no other performance security required.
• Prices fixed for the contract; adjustments only for incidental services, VAT changes and exchange-rate fluctuations.
• Foreign-currency component: bidder must separate overseas and local costs; exchange rate variations considered only on the foreign portion using rates from ABSA or xe.com against the rate at signing of SBD 7.1.
• Price adjustments for additional services must be substantiated (e.g., inflation, technology refresh, exchange rates); iThemba LABS may obtain three market quotes to verify pricing.
• Contract value is the cumulative value of all purchase orders issued and paid.
• Purchase orders are issued per batch/lot; iThemba LABS guarantees funding for each order.
• Termination for default: iThemba LABS may appoint an alternative provider at the defaulting bidder's cost; the defaulting bidder must settle resulting damages.

• CSD registration: required; include the Master Registration Number (Supplier Number) in the bid so tax status can be verified on the CSD.
• Tax compliance: verified via the CSD; non-resident bidders must obtain a Confirmation of Tax Obligations letter from SARS after submitting the SBD 1 tax questionnaire.
• SBD 1 (Invitation to Bid): signed and completed.
• SBD 4 (Declaration of Interest): signed and completed.
• SBD 6.1 (Preference Points Claim): signed and completed with B-BBEE certificate or sworn affidavit.
• Resolution authorising the signatory (unless owner/partner/managing director).
• B-BBEE preference points claimed per PPPFA 2000 and 2022 Regulations; specific levels not stated.
• Mandatory reference: at least one contactable reference for supplying a GMP-compliant glove box for an At-211 (Atley C100 or similar) synthesis unit.
• Full completion of the specification checklist with "Yes" or "No" responses; any "No" requires a stipulated alternative.
• No CIDB grade, CIPC registration or local-content percentage is specified.

• Glove box must provide a ventilated work compartment to contain 211At vapour and particles.
• Work compartment pressure must be maintained at -40 Pa relative to the lab; differential pressure gauge with alarm required.
• Intake and exhaust air must be filtered with carbon filters to prevent contaminated air leakage, and HEPA filters for product protection.
• Manual shut-off valves allow isolation in emergencies and pressure integrity testing.
• Radiation dose monitoring system required inside the compartment.
• Air exchange: minimum 20 air changes per hour.
• Exhaust venting connected to HVAC or alternative solution per local radiation safety standards.
• Material pass-through must have dedicated ventilation.
• Gloves must be butyl rubber, resistant to chloroform, melting point above 105°C.

Contract period: five years, from the date the SBD 7.1 contract form is fully signed.

Special conditions:

• Performance security required only if an upfront deposit exceeds R 1 million (bond equal to the deposit).
• Packing must prevent damage during transport and storage.
• Payment within 30 days of invoice; earlier if accompanied by signed delivery validation documents.
• Prices fixed; adjustments for incidental services, VAT changes and exchange rates.
• Price adjustments shared equally between the parties; additional services priced with substantiation and subject to negotiation and market verification.
• Foreign price component separated from local costs; exchange rate variations based on ABSA or xe.com rates.
• Purchase orders authorise work; iThemba LABS guarantees funding for each order.
• Contract value = cumulative purchase order values.
• Termination for default: iThemba LABS may appoint an alternative provider at the bidder's cost; defaulting bidder must settle damages.

Performance levels:

• Delivery of specified services: verified jointly against specifications; penalty per GCC 22.
• Timeous delivery: delay of two weeks or more from agreed date triggers penalty per GCC 22.
• On failure: joint root-cause investigation, prompt correction, status reporting and preventive measures.

Due diligence: iThemba LABS may conduct site visits and inspections at any time during the contract; supply chain due diligence allowed.

Communication: must include contract and purchase order numbers; no action without the contract number.

Intellectual property: all contract IP vests with the purchaser unless agreed otherwise in writing; supplier grants a fully paid-up, irrevocable, non-exclusive licence for its background IP.

Mandatory administrative documents for evaluation qualification:

• SBD 1 (signed and completed)
• SBD 4 (signed and completed)
• SBD 6.1 (signed and completed, with B-BBEE certificate or sworn affidavit)
• Resolution authorising signatory (unless owner/partner/managing director)

Mandatory technical/eligibility items:

• At least one contactable reference for a GMP-compliant glove box suitable for an At-211 Atley C100 or similar synthesis unit
• Completed specification checklist ("Yes"/"No" with alternatives for "No")
• Presentation of proposed system elements

Pricing competition document:

• SBD 3.2 (Pricing Schedule) in the prescribed format, in a separate envelope

General bid conditions:

• Bidder warrants reading and accepting each page of the bid document.
• CSD registration and Master Registration Number required.
• Clarification requests answered within 2 working days; responses shared with all registered bidders.
• NRF not liable for response preparation costs.
• No counter proposals.
• Collusion, fraud, corruption or fronting disqualifies; fronting invalidates the bid and can lead to a ban of up to 10 years.
• Declaration of interest: bidder must disclose any conflict of interest and promptly update disclosures; false declarations disqualify.
• The bidder with the highest combined score is nominated for award.
• NRF may cancel the bid if the need lapses, no bid meets the specification, a material irregularity occurs, or pricing is outside the market range without negotiation.